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However, consumers should exercise caution and consult healthcare providers before using such supplements, as their safety and efficacy might not be well-established

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These include the induction of fever, an acute phase response in the liver characterized by leukocytosis and the production of acute-phase proteins such as C-Reactive Protein (CRP), and the differentiation or activation of T cells, B cells, and macrophages (Ishartadiati 2009

The FDA isn't bound by the committee's recommendations but typically follows them