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Maximum Responder Rate (20%+ Loss)# Recommendation : CagriSema Reason : 60% of CagriSema patients achieved at least 20% weight loss in REDEFINE 1, a higher responder rate than tirzepatide's across-trial data, though cross-trial comparison has limitations

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However, when the intestinal tract is bypassed or modified as it is with the gastric bypass or duodenal switch, there is less surface area for this process to occur