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Lower estrogen, reduced activity over time, and menopause-related sleep disruption often work together to drive steady weight gainabout 1.5 pounds per year on average after menopause

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Thermal sensitivity testing demonstrated that as a group, at baseline, the subjects exhibited a reduction of function of cold detection threshold of all three regions tested, and reduced function in warm detection threshold in the foot and hand (Figure 7)

If you are lean and must use the thigh, always pinch the skin, use a 45-degree angle, and consider a shorter needle (3/8 inch instead of 1/2 inch) to reduce intramuscular injection risk

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