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Take it when you need methylation support based on how you feel, your homocysteine levels, and your symptoms

Both vitamin C (L-ascorbic acid in particular) and copper peptides are oxidation-sensitive, and very low-pH vitamin C formulas can destabilize the copper-peptide complex

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Picomolar to nanomolar activity suggests high receptor affinity and potent biological signalling, which is encouraging for topical delivery where only a fraction of applied compound reaches the follicle