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2021. NNMT inhibition reduces obesity and diabetes risk

The peptide also does not stimulate IGF-1 production, avoiding the growth-promoting and potentially mitogenic effects associated with IGF-1 elevation

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AOD-9604, MOTS-c, and Tesamorelin are sometimes examined together in research contexts because each engages a distinct biological pathway hGH-fragment signaling, mitochondrial energy regulation, and the growth hormone axis, respectively rather than because they are interchangeable