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10.1136/tobaccocontrol-2016-052961

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The study Vapors Produced by Electronic Cigarettes and E-Juices with Flavorings Induce Toxicity, Oxidative Stress, and Inflammatory Response in Lung Epithelial Cells and in Mouse Lung found: There are approximately 10 15 free radicals in a puff of conventional cigarette smoke in addition to heavy metals nanoparticles which have also recently been shown in e-cig aerosols to similar levels per puff [10,16]

As for any flight, its wise not to wait too long with booking as the fares go up coming closer to the departure date