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For example, athletes with high metabolic demands, vegans who consume no dietary B12, or individuals with chronic malabsorption issues like Crohns disease may find they feel their best with a bi-weekly (every two weeks) injection
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Hydroxocobalamin is the form the NHS uses because it lingers in the body longer than cyanocobalamin, and its pharmacology supports dosing intervals of up to three months once levels are stable
However, consumption of any type of vegetarian diet dramatically increases the prevalence of vitamin B 12 deficiency in individuals across all age groups (127, 128)