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They restored sperm quality, re-established redox homeostasis, normalized steroidogenic gene expression, and preserved the structural integrity of reproductive tissues

288,289 In diabetic conditions, these macrophages can transition to a proinflammatory phenotype, accumulate, and contribute to nerve damage

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The systemic administration of nanoparticles loaded with doxorubicin, furthermore, inhibited tumor-growth of SCC7 head and neck cancer xenograft models by over 70% compared to non-treated control mice and by over 40% in comparison with conventional free doxorubicin-treated mice without severe side effects