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Konturek SJ, Brzozowski T, Konturek PC, et al

Nr-CAM, a cell adhesion molecule, is involved in interactions between nerve cells, and its abnormal expression may lead to changes in neuronal adhesion and signaling, affecting cognitive function and learning abilities [79]

Genes were amplified using oligonucleotides (Table S1) and PowerUp SYBR green Master Mix following the manufacturers protocol (Applied Biosystem)

Specifically, MCT1 is abundantly expressed in adipose cells, and selective blockade agents have been shown to cause cell-intrinsic lactate retention, thereby stimulating adipocyte apoptosis, promoting pro-inflammatory cytokine release, and exacerbating insulin resistance in both adipose and surrounding tissues [144]