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Some relevant physiological evidence comes from analysis of catalase-deficient plants which, as noted above, are useful systems for probing the potential functions of reductive H 2 O 2 -metabolizing pathways in vivo (Dat et al., 2001

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 356:147154

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Injections of rhIGF-1 resulted in a fraction of unbound IGF-I in serum despite the impaired proteolysis of IGFBP-5 and IGFBP-3 (133)