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The growing body of preclinical and clinical evidence continues to attract new investigators to the field each year
Zhang, S., Lachance, B
Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions
As shown in Figure 9B, the common targets of main ingredients and AD in FRP are mainly enriched in signal transduction, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, negative regulation of the apoptotic process, response to the drug, positive regulation of gene expression, positive regulation of cell proliferation, response to xenobiotic stimulus, positive regulation of transcription, DNA-templated, positive regulation of MAPK cascade
GLP-1 and GIP both participate in incretin biology, while glucagon receptor activation may influence energy expenditure, fat oxidation, and liver metabolism
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