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The report of the US Surgeon Generals first Smoking and Health in 1964 was seen as the landmark report that made it known to a wide public that smoking cigarettes has dangerous health effects, including lung cancer and heart disease

Next, Horn reviewed the supposed advantages of the low-tar scheme against the background of what he said was a growing public conviction that cigarette smoking really was harmful to health, and pointed out that many smokers were adjusting their smoking habits accordingly

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"We also don't know how harmful trace levels can be." Thomas Glynn, the director of science and trends at the American Cancer Society, said there were always risks when one inhaled anything other than fresh, clean air, but he said there was a great likelihood that e-cigarettes would prove considerably less harmful than traditional smokes, at least in the short term