Senescent cells are cells that have permanently halted their cell cycle ('replicative arrest') but resist apoptosissometimes called 'zombie cells.' They accumulate with age in multiple tissues and secrete a pro-inflammatory cocktail called the Senescence-Associated Secretory Phenotype (SASP), containing IL-6, IL-8, MMP-3, MMP-9, TNF-, and other factors that damage surrounding healthy tissue
For systemic tissue repair (tendons, ligaments, joints), subcutaneous injection is more reliable for both peptides
10.1126/science.279.5355.1368 83 MageeJ
This is the most common question we hear, and the honest answer is: it depends on your diagnosis
Lehmann ML, Brachman RA, Martinowich K, Schloesser RJ, Herkenham M