Formulated with 0.9% benzyl alcohol (9 mg/mL) as a bacteriostatic preservative, it helps inhibit microbial growth, making it ideal for repeated withdrawals when proper sterile technique is followed
Loren Pickart identified the compound in the 1970s and spent decades documenting its role in tissue repair, collagen synthesis, and inflammatory modulation
Studies examining safety and tolerability in rodents have generally not reported concerning toxicity signals at doses producing metabolic benefits, though comprehensive toxicology studies and long-term safety data are limited
What do preclinical timelines show
When to consider the diagnosis of EDS EhlersDanlos syndrome needs to be considered when, in the absence of another explanation, one or more of the following occur: late walking with joint hypermobility abnormal bruising and bleeding unexplained vessel rupture or dissection tissue fragility, atrophic scarring or skin hyperextensibility symptomatic joint hypermobility dislocations Hollow organ rupture A systematic approach to the patient with suspected EDS is essential to avoid costly and unnecessary investigations, but first one needs to be aware of the different subtypes within this group and their diagnostic features