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GHK was first identified in 1973 by Pickart as a factor in human plasma that altered the gene expression of cultured liver cells

Circadian regulators, brain and muscle ARNT-like 1 (BMAL1) and period circadian regulator 1 (PER1), affect pigmentation timing, ensuring hair color precision

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Deficiencies lead to weakened bones, muscle discomfort, and an array of other symptoms that require careful monitoring

In addition, expression of HGF can be detected all over the body