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Reasonable markers to track: waist circumference, weight, resting heart rate, sleep quality, and a basic liver panel (ALT, AST) before and after long cycles

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Mechanistic Studies Subsequent research has explored the mechanisms by which NNMT regulates metabolism, with studies demonstrating that NNMT activity reduces cellular NAD+ availability, affects SAM-dependent methylation reactions, modulates sirtuin activity, and influences adipocyte differentiation and function