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Diniz Vilela et al., 2016

Refrigeration (2-8 degrees C) is preferred for long-term storage (months) Light: Keep away from direct sunlight and UV exposure

This review summarizes the most recent evidence concerning biologic and toxicologic effects of acyl glucuronide metabolites of various drugs and discusses their relevance for drug monitoring

NRF2 reprograms cellular metabolism to funnel metabolic intermediates into antioxidant pathways While NRF2 regulates the expression of antioxidant and NADPH-generating enzymes, metabolic intermediates are required to support these pathways