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Reducing SLC25A40 destabilizes ISC-rich ETC subunits most predominantly Complex I elevates mitochondrial and cellular ROS, induces Gclc/Gclm , and diminishes IL-1 and IL-10 transcription without affecting NLRP3-mediated pyroptosis

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Valproic acid, one of the most commonly prescribed epilepsy treatment drugs, also used to treat certain psychological conditions such as bipolar disorder, is a known inhibitor of folic acid

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