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Another study involving 51 women found that curcumin improved insulin sensitivity (QUICKI index) after six weeks of supplementation but did not significantly alter lipid or glycemic markers compared to placebo [203]

Further research confirmed that administration of the extract alleviated the severity of liver injury (Sharifudin et al., 2013)

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Integrated Lipidomics and Metabolomics Analysis of Tears in Multiple Sclerosis: An Insight Into Diagnostic Potential of Lacrimal Fluid

Furthermore, activation of the CREB response element at Ser133 of the CREB protein leads to upregulation of BCL-2 and BDNF gene expression