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In principle, decreased extracellular potassium entails myocardial hyperexcitability, with the potential to develop re-entrant arrhythmias in the skeletal muscle, hyperpolarization of the resting membrane potential, and a greater-than-normal stimulus for depolarization of the membrane in order to initiate an action potential [106]

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TNF-alpha: Inflammation, Chronic Diseases, and Genetic SusceptibilityTNF-alpha is a key inflammatory cytokine linked to autoimmune, cardiovascular, mood, and neurodegenerative diseases