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The peptide enhances growth factor expression including fibroblast growth factor (FGF) and epidermal growth factor (EGF), while simultaneously reducing pro-inflammatory cytokines like TNF- and IL-6

It has been extensively characterised in preclinical in-vitro and in-vivo models for its cytoprotective, angiogenic, and anti-inflammatory properties across a range of tissue types

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both are inflammatory and may cause scarring