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The generation of oxidative DNA lesions, such as 8-oxoguanine (8-oxoG), is linked to the development of various cancers, including melanoma, while the accumulation of these lesions can compromise genomic stability, leading to mutations and the eventual transformation of normal cells into malignant ones 53

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The timeline for tendinopathy improvement tends to follow a pattern where initial pain reduction occurs within the first week, with progressive functional improvement over 4 to 6 weeks

Solleiro-Villavicencio H, Rivas-Arancibia S

Acknowledgments This work was supported by grants from Fundao Carlos Chagas Filho de Amparo Pesquisa do Estado do Rio de Janeiro (FAPERJ) and Oncobiologia Program