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Research Limitations To our surprise, most studies have not explained how they determined the optimal dosage

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Pregnant or Breastfeeding Women Supplement use during pregnancy or breastfeeding requires medical supervision Hormonal and nutritional needs differ during these periods A doctor can assess whether supplementation is appropriate or should be avoided Self-medication during pregnancy or lactation is not recommended

Rare but serious risks include acute pancreatitis and kidney injury, though these occur at low frequencies in clinical populations