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However, these cells convert rapidly to a pro-regenerative phenotype (Ly6C lo ) [103] that is essential for recovery by removing cell debris and promoting regeneration [104, 105]

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Schematic representation of the mechanism of Sirt1 associated Adriamycin-resistance in DLBCL cells

Because the area may be numbed with a topical anesthetic before the Sculptra injections, patients experience minimal discomfort during the procedure