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Targeted therapy and immunotherapy for lung cancer

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Exposure to mercury through contaminated soil, air, or water initiates a cascade of pathological events that lead to organ damage, including platelet activation, oxidative stress, enhanced inflammation, and direct injury to critical cells such as cardiomyocytes and endothelial cells

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Combining this approach with CRISPR screening, we identified SLC33A1 as the major ER GSSG exporter in mammalian cells