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There is also an increasing trend of socially responsible marketing, emphasizing the reduced harm associated with smokeless tobacco compared to traditional smoking

In order to reduce the incidence of allergic primin contact dermatitis, a primin-free Primula obconica Hance was developed.118 Although its introduction reduced significantly the cases related to cultivars, it still remains as an important contact allergen, justifying its maintenance in the standard series

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55 In another investigation, widespread uptake of NNK was demonstrated in a group of economically disadvantaged schoolchildren, and the range of levels varied over 90-fold

Tobacco tar refers to the layer of brown, greasy residue that accumulates in the mouthpiece used by a smoker, commonly known as tar