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Thyroid Function : Rare reports of temporary thyroid function changes, though causation remains unclear in research literature

The FDA's Category 2 classification makes clinical development in the United States more difficult, not less

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Adverse Effects In the phase 2 TROPION-Lung05 trial, treatment-related adverse effects (TRAEs) of grade 3 or higher were observed in 28.5% of patients, and the most common included stomatitis (9.5%), nausea (2.2%), and decreased appetite (2.2%)