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CVD is a general term that describes a disease of the heart or blood vessels, such as coronary heart disease

Acknowledgements We thank the University of Maryland Electron Microscopy Core Imaging Facility for transmission electron microscopy consultation and training, Nagendra Yadava and Brandon Carter-Cooper at the University of Maryland Translational Laboratory Shared Service for respirometry consultation, the Ndufa1 antibody, and recombinant perfringolysin O, Amanda Law for shared equipment, Victoria Meadows, Jessica Fluharty, Henry Haller, Erin Weinhold, and Peter Moon for technical assistance, and Scott Thompson for editorial feedback

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[12] Very high cumulative exposure over months may encourage calcium deposition in soft tissues such as the renal parenchyma or coronary arteries, an outcome implicated in observational studies linking supra-physiological 25-hydroxyvitamin D levels with vascular calcification and heightened fracture risk in frail elders

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