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Another study investigated the anti-inflammatory and ocular surface-protective effects of 1,5-dicaffeoylquinic acid (1,5-diCQA), a polyphenolic component from Pseudognaphalium affine , on DED symptoms

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These findings suggest that caudatins antiproliferative activity arises from simultaneous modulation of both pro-proliferative and pro-survival signaling nodes

It therefore appears likely that Tau and A can be induced into states that promote a generalized antimicrobial response, supported by the ability of a variety of bacterial DNAs to promote Tau aggregation in vitro (Tetz et al., 2020)