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In contrast, LPS-induced Raw 264.7 cells (PBS) display significantly reduced fluorescence, suggesting that LPS has impaired the mitochondrial membrane potential of Raw 264.7 cells

BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons

This increased permeability allows lipopolysaccharides (LPS), food antigens, and microbial byproducts (PAMPs) to translocate into circulation, triggering systemic immune activation and placing further burden on mast cells 18

Abstract Major depressive disorder (MDD) is severely disabling, and current treatments have limited efficacy

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