Gabery S, Glendorf T, Ballarin-Gonzalez B, Pedersen K, Kruse T, Raun K, Kuhre RE
Introduction According to the World Health Organization (WHO), sepsis leads to about 6 million deaths per year worldwide ( To study the pathogenesis and therapeutic targets in sepsis, several animal models have been widely used, but cecal ligation puncture (CLP) procedure is considered one that most closely resembles human sepsis ( Aedes aegypti improved mice survival through immunomodulatory and antimicrobial effects associated with lower oxidative status (decreased lipid peroxidation and increased antioxidant defense) ( Agaricus brasiliensis (Ab) ( Ab is a mushroom rich in bioactive compounds such as organic acids, amino acids, phenolic compounds and polysaccharides such as -glucans ( Therefore, considering sepsis as one of the major global public health challenges, the urgency for new therapeutic alternatives and the immunomodulatory properties of Ab, the aim of this study was to evaluate for the first time the effects of prophylactic administration of aqueous extract of Ab on survival, immunological and oxidative parameters in a murine sepsis model
Reproductive Health: FOXO4-DRI shows promise in improving reproductive health by targeting senescent Leydig cells, which contribute to age-related hypogonadism and reduced fertility
As the severity of OSAHS progresses, there is a gradual decline in the proportion of type I fibers, accompanied by a corresponding increase in type II fibers (21)
NPs are materials whose sizes fall from 1 to 100 nm (18, 19)
