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Graphical Abstract Similar content being viewed by others Introduction Glutathione (GSH) is the most abundant intracellular antioxidant, which plays vital roles in cells, including maintaining redox state, drug detoxification and protecting cells from free radicals, peroxides and toxins

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Emerging research on non-selenium GPx like GPx7 and GPx8 shows their integration in endoplasmic reticulum stress responses, broadening the antioxidant web

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