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Most people following a varied diet get the recommended amount, but vegans, people with certain gut conditions and older adults who absorb nutrients less efficiently may need supplements

Most people get enough vitamin B12 in their diet, but a deficiency may occur in certain health conditions (such as poor nutrition, stomach/intestinal problems, infection, cancer)

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References Alikhani N, Ankarcrona M, Glaser E (2009) Mitochondria and Alzheimers disease: amyloid-beta peptide uptake and degradation by the presequence protease, hPreP