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We also found that ARID1A is crucial for NRF2-mediated regulation of target genes beyond SLC7A11 and GPX4, such as HMOX1, FTL, and FTH1

It upregulates the expression of vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), and their respective receptors at sites of injury, directly promoting angiogenesis and epithelial repair

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