glutathione and apoptosis depletion induces oxidative injury via TRPM2 channel activation in renal collecting duct cells Knockdown of microsomal glutathione S-transferase

Rational design in photopharmacology with molecular photoswitches

Dry skin, rough skin, uneven body tone, body pigmentation, winter dryness, sun-damaged skin

GSHGSSG redox cycle The reversible conversion between glutathione (GSH) and its oxidized form, glutathione disulfide (GSSG), constitutes one of the most core cellular redox buffering systems

Glutathione is one of the most important antioxidants your body produces naturally to protect its cells and maintain essential functions

Methods Computer-aided molecular design, synthesis, and characterization All the computer-aided molecular design studies were performed in SZMAP/GamePlan 37 and vBrood 38 modules in OpenEye software and Molecular Operating Environment, MOE 39