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A weakened heart may not pump blood efficiently, which can lead to symptoms such as: Shortness of breath, especially with activity or when lying down Fatigue or weakness Swelling in the legs, ankles, feet or abdomen (fluid retention) Rapid or irregular heartbeat Dizziness or fainting Persistent coughing or wheezing, sometimes with pink-tinged mucus Difficulty exercising or climbing stairs These may indicate heart failure or another form of heart disease and should be evaluated by a healthcare provider

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Skin whitening or skin lightening entails removing dark spots, black markings, skin imperfections, and scars

Epigenetic Effect: They influence gene expression , turning specific genes on or off

A recent study using murine melanoma cell culture also exhibited reduced melanogenesis by the treatment of polyhydroxy flavones 115