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This higher activity results from the insensitivity of ETC to FCCP treatment and is consistent with the limited reserve capacity of Gclc -deficient FoB (Fig

Blood 120 , 48824891 (2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] Culver G

In one example, GSH-driven nanoparticle disintegration releases indomethacin to inhibit PTGS2 while reducing Pt 4 + to cytotoxic Pt 2 + , thereby amplifying cisplatin-induced pyroptosis in pancreatic cancer 218