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Steatosis was defined as either microvesicular, if the vacuoles were multiple within the cytoplasm and did not indent the nucleus, or macrovesicular, if there was a single vacuole with displacement and distortion of the nucleus

1 It cannot be manufactured by humans and must be regularly obtained from the ingestion of animal proteins or fortified cereal products

In a Phase III trial, Winrevair hit the primary endpoint, eliciting a statistically significant and clinically meaningful improvement in the 6-minute walk distance test after 24 weeks

The difference comes down to manufacturing environment, formulation specifics, and testing depth

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