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That is important, because it confirms that VEGFR2 is not just one of many mechanisms, but truly a causal pathway

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Following xenobiotic exposure, the Nrf2/Keap1 pathway is activated, releasing Nrf2 and causing it to translocate into the nucleus where it forms a heterodimer with its partner sMAF oncogene homolog

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doi: 10.1016/j.jaci.2007.01.016 81 OSullivanDSaninDEPearceEJPearceEL

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