Many patients question whether continuing is worth it
Have you noticed a change in your normal state, including changes in weight or pain in the joints
NICE-recommended weight management strategies include: Dietary intervention aiming for a 600 kcal/day deficit through reduced portion sizes, limiting energy-dense foods, and increasing fruit and vegetable consumption Physical activity building up to 150300 minutes of moderate-intensity aerobic activity weekly, plus muscle-strengthening activities on at least two days weekly, in line with UK Chief Medical Officers' guidelines [10] Behavioural approaches including self-monitoring, goal-setting, and addressing emotional eating patterns Commercial weight management programmes such as those meeting NICE quality standards (QS127) Very-low-calorie diets in specific circumstances, under clinical supervision and for limited periods For patients with a BMI 30 kg/m (or 27.5 kg/m in those of South Asian, Chinese, or other Asian family origin) who have not achieved adequate weight loss through lifestyle measures alone, pharmacological interventions may be considered
[DOI] [PMC free article] [PubMed] [Google Scholar] 147.Lin G.L., Chang H.H., Lien T.S., Chen P.K., Chan H., Su M.T., Liao C.Y., Sun D.S
The copper ion may dissociate from the GHK tripeptide, and free copper ions are pro-oxidant
