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Notably, MSNs with positively charged groups (PCGs) have a unique feature that can adsorb the single-stranded DNAs (ssDNAs) at neutral pH 34

elevated plasma levels of these components indicate glycocalyx shedding [14,15,16]

The measurement of paracellular permeability is usually quite straightforward since the movement of ions and charged organic molecules can be measured as an electrical current and the movement of neutral molecules can be measured by assaying their concentration in the bloodstream or urine or in a compartment equivalent to the subepithelial space in mounted or perfused tissue or in cultured cells grown on permeable substrates

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