1980s : Advances in immunology lead to a better understanding of the autoimmune nature of Graves disease, spearheaded by researchers at institutions like the National Institutes of Health (NIH)
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Assessment of quality of included studies To evaluate the quality of evidence (QoE) of the included studies three tools were used: the Cochrane Risk of Bias of RCTs [24], the JADAD score [25], and CONSORT guidelines [26]
To date, most clinical trials investigating antioxidant supplementation have been relatively short in duration and therefore insufficient to address its potential role in modulating the processes of aging and longevity
