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For instance, in one 1960s study of intravenous NAD+ for addiction, patients who received a fast IV drip experienced immediate headache and shortness of breath, whereas those given the same dose at a slower drip rate (under ~35 drops/min) had no distress

References Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov DS, Brcic L, et al

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