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Other oxidative stress response transcription factor deletion strains such as rrt5, hcm1, smp1 , msn2, msn4 were not showing sensitivity towards 5-OP except elg1 and tbf1 showing a mild sensitivity (Fig S4)

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Levels of GHK naturally decline as we age and research has demonstrated that this peptide can stimulate synthesis of collagen, elastin, and glycosaminoglycans in the skin