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Cigarette Smoking and Airway Inflammation Neutrophilic airway inflammation and release of neutrophil chemoattractant cytokines, including IL-8, have been observed to be associated with smoke exposure, with sputum IL-8 concentration being related to percent-predicted forced expiratory volume in 1 second (FEV 1 ) in smoking asthmatics [39]

Flue-cured nicotine, a manufacturing practice that can be changed at any time, is nearly solely responsible for the current global lung cancer epidemic

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