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Redox active plasma iron in C282Y/C282Y hemochromatosis

Queval G, Thominet D, Vanacker H, Miginiac-Maslow M, Gakire B, Noctor G (2009) H2O2- activated up-regulation of glutathione in Arabidopsis involves induction of genes encoding enzymes involved in cysteine synthesis in the chloroplast

Clone MD106 Isotype IgG1k Host species Mouse Species Reactivity Human Cellular Localization Cytoplasm Positive Control Kidney, liver or placenta tissues, HeLa, MCF7 or HepG2 cells Applications IHC, WB Intended Use Research Use Only

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4.3 Multifaceted roles of GPXs in plant biological processes The direct association of GPX2, GPX3, GPX4, GPX5, GPX7, and GPX8 with glutathione metabolic processes ( Figure 5 ) suggests that the proteins can use glutathione as an electron donor in reducing H 2 O 2 or organic and lipid hydroperoxides to maintain plant cell redox homeostasis ( Supplementary Table S2 ) (Yang et al., 2005)