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May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose
Binds to highly phosphorylated inositol phosphates such as inositolhexakisphosphate (InsP6) which is essential for its necroptotic function
Uniprot: P22304
Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs
and regulates macrophage function
RPA70 Monoclonal Antibody-MB11544 Nucleic Acid Tranfection May be involved in immuneRPA70 Monoclonal Antibody Sizes: 50l, 100l Catalogue Numbers: MB11544 50, MB11544 100 Product: 50mM Tris Glycine(pH 7. 4), 0. 15M NaCl, 40% Glycerol, 0. 01% Sodium azide and 0. 05% BSA Swiss Prot: P27694 Host: Rabbit Reactivity: Human Applications: WB,IHC F,IHC P,ICC IF,IP All Applications: WB: 1 500 1 1000 IHC: 1 50 1 100 IF: 1 50 1 200 IP: 1 20 Background: Plays an essential role in several cellular processes in DNA metabolism including replication,