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Oxidation can still occur if the vial isn't properly sealed (oxygen exposure oxidises the copper ion), but the rate is negligible in vacuum-sealed or nitrogen-purged vials

Additionally, catechin exhibits anti-inflammatory properties by suppressing microglial activation reducing TNF-, IL-1, and IL-6 levels

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Research shows that SAMe can also support cognitive function by stimulating increased activity of serotonin and dopamine

Additional neurotoxic mechanisms associated with gutbrain axis dysfunction include MP-induced disruption of hippocampal circadian rhythms and altered neurotransmitter metabolism (112, 113)