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The pyrophosphate, formed from the hydrolysis of the two high-energy bonds in ATP, is immediately hydrolyzed to two molecules of P i by inorganic pyrophosphatase

Both strains have decent research support

Previously, selective antitumor activity was observed in H1299 lung cancer cells over WI38 normal lung fibroblasts cells, and the principle and mechanism of GSH-responsive AP probe-net had been briefly confirmed in vitro [11]

however, aggregates of TTR, including oligomeric forms, have previously been linked to cytotoxicity [81,82,83,84,85] supporting the possibility that misfolded TTR may contribute to this response

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