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A Phase 2 study published in the New England Journal of Medicine in 2023 (Jastreboff et al.) reported substantial weight loss in participants with obesity

Dual Diagnosis Treatment People with mental health disorders are more likely to turn to substances as a way to self-medicate and cope with their symptoms

This selectivity makes it ideal for combination with Tirzepatide, where appetite suppression is a desired outcome

The procedure is fast, and any discomfort is generally mild and temporary

A VEGF-independent pathway involving Src kinase and caveolin-1-mediated eNOS activation was additionally proposed as a parallel angiogenic mechanism engaged by BPC157